This really is the best homestyle meatloaf recipe ever! If you are a meatloaf enthusiast like I am, I’m sure you’ll agree.
This homestyle meatloaf recipe is inspired by the wonderful meatloaf my mother used to make when I was a child. Topped with ketchup, this recipe is pure comfort food bliss.
I’m sure I’m not alone in my love of meatloaf. It’s hard to find anyone that doesn’t like it.
Making the Best Moist Meatloaf Recipe
If you want a deliciously moist homestyle meatloaf recipe, then it all starts with the meat. You must use lean ground beef or lean ground turkey. Not too mention that eating lean meat is healthy for you.
We have been busy experimenting in the kitchen to bring you this classic homestyle meatloaf recipe. After a ton of trial and error, we think we finally got it down. The main take away is: a simple meatloaf is a great meatloaf.

How Long to Cook Meatloaf?
One of the nice things about this amazing meatloaf recipe is that it can be prepared in a relatively short amount of time. Once made, it can be reheated for several days after. Traditional moist meatloaf recipes usually cook for 50-55 minutes at 350.
Best Moist Meatloaf Recipe Ever!
Cook Time 55 minutes
Total Time 55 minutes
Servings 4 People
Ingredients for Meatloaf
- 1 pound lean ground beef
- 1/2 tsp Fresh oregano
- 1/2 cup Panko bread crumbs
- .5 tbsp White Onion
- 2 Eggs
- 1/4 cup Roma tomatoes
- 1/4 cup Pecorino Romano Cheese, grated
- 1 tbsp basil
- 1/2 tbsp garlic powder
- pinch Salt and Pepper
- 1/4 cup Ketchup
Homestyle Meatloaf Cooking Instructions
1) Preheat oven to 350 degrees Fahrenheit.
2) Mix all ingredients in a large bowl.
3) Form mixture into a rectangular meatloaf baking pan.
4) Add desired amount of ketchup and spread evenly.
5) Cook for 50 minutes.
6) Let sit for 10 minutes
7) Enjoy!